Long Wavelength Anomalous Diffusion Mode in the 2D XY Dipole Magnet

In 2D XY ferromagnet the dipole force induces a strong interaction between spin-waves in the long-wavelength limit. The major effect of this interaction is the transformation of a propagating spin-wave into a diffusion mode. We study the anomalous dynamics of such diffusion modes. We find that the Janssen-De Dominics functional, which governs this dynamics, approaches the non-Gaussian fixed-point. A spin-wave propagates by an anomalous anisotropic diffusion with the dispersion relation: $i\omega{\sim}k_{y}^{\Delta_y}$ and $i\omega{\sim}k_{x}^{\Delta_x}$, where ${\Delta_y}=47/27$ and ${\Delta_x}=47/36$. The low-frequency response to the external magnetic field is found.Comment: 34 pages, RevTeX, 2 .ps figures, the third figure is available upon reques

Inter‐ and intraindividual variability of urinary dextromethorphan/dextrorphan (DM/DX) ratios in CYP2D6 extensive metabolizers (EMS) with one or two active alleles

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109829/1/cptclpt200481.pd

Two dimensional electron gas driven by strong alternating electric field

2D Fermi liquid driven by uniform alternating electric field at zero temperature may remain in quantum coherent non-equilibrium state. We develop a quasistatic approximation for strong and slow ac-fields and solve the problem of driven disordered 2D electron gas in high non-overlapping Landau levels. The broadening of Landau level has the Lorentz form and is inversely proportional to the amplitude of the ac-field. In the absence of electron-phonon interaction the electron distribution function is constant within the last Landau level and the diagonal dc-conductivity is zero. For weak electron-phonon interaction the dc-conductivity is anisotropic. A kinetic transition from the phonon cooling to the phonon heating is predicted.Comment: 8 pages, 1 figure REVTE

Multicomponent dense electron gas as a model of Si MOSFET

We solve two-dimensional model of $N$-component dense electron gas in the limit of large $N$ and in a range of the Coulomb interaction parameter: $N^{-3/2}\ll r_s\ll 1$. The quasiparticle interaction on the Fermi circle vanishes as 1/N. The ground state energy and the effective mass are found as series in powers of $r_s^{2/3}$. In the quantum Hall state on the lowest Landau level at integer filling: $1\ll\nu<N$, the charge activation energy gap and the exchange constant are found.Comment: 10 pages, 4 figure

Saquinavir Loaded Acetalated Dextran Microconfetti – a Long Acting Protease Inhibitor Injectable

Since the adoption of highly active antiretroviral therapy, HIV disease progression has slowed across the world; however, patients are often required to take multiple medications daily of poorly bioavailable drugs via the oral route, leading to gastrointestinal irritation. Recently, long acting antiretroviral injectables that deliver drug for months at a time have moved into late phase clinical trials. Unfortunately, these solid phase crystal formulations have inherent drawbacks in potential dose dumping and a greater likelihood for burst release of drug compared to polymeric formulations

Continuum limit, Galilean invariance, and solitons in the quantum equivalent of the noisy Burgers equation

A continuum limit of the non-Hermitian spin-1/2 chain, conjectured recently to belong to the universality class of the noisy Burgers or, equivalently, Kardar-Parisi-Zhang equation, is obtained and analyzed. The Galilean invariance of the Burgers equation is explicitly realized in the operator algebra. In the quasi-classical limit we find nonlinear soliton excitations exhibiting the $\omega\propto k^z$ dispersion relation with dynamical exponent $z=3/2$.Comment: 12 pages, latex, no figure

Aging in a Two-Dimensional Ising Model with Dipolar Interactions

Aging in a two-dimensional Ising spin model with both ferromagnetic exchange and antiferromagnetic dipolar interactions is established and investigated via Monte Carlo simulations. The behaviour of the autocorrelation function $C(t,t_w)$ is analyzed for different values of the temperature, the waiting time $t_w$ and the quotient $\delta=J_0/J_d$, $J_0$ and $J_d$ being the strength of exchange and dipolar interactions respectively. Different behaviours are encountered for $C(t,t_w)$ at low temperatures as $\delta$ is varied. Our results show that, depending on the value of $\delta$, the dynamics of this non-disordered model is consistent either with a slow domain dynamics characteristic of ferromagnets or with an activated scenario, like that proposed for spin glasses.Comment: 4 pages, RevTex, 5 postscript figures; acknowledgment added and some grammatical corrections in caption

Giant Magnetoresistance Oscillations Induced by Microwave Radiation and a Zero-Resistance State in a 2D Electron System with a Moderate Mobility

The effect of a microwave field in the frequency range from 54 to 140 $\mathrm{GHz}$ on the magnetotransport in a GaAs quantum well with AlAs/GaAs superlattice barriers and with an electron mobility no higher than $10^6$ $\mathrm{cm^2/Vs}$ is investigated. In the given two-dimensional system under the effect of microwave radiation, giant resistance oscillations are observed with their positions in magnetic field being determined by the ratio of the radiation frequency to the cyclotron frequency. Earlier, such oscillations had only been observed in GaAs/AlGaAs heterostructures with much higher mobilities. When the samples under study are irradiated with a 140-$\mathrm{GHz}$ microwave field, the resistance corresponding to the main oscillation minimum, which occurs near the cyclotron resonance, appears to be close to zero. The results of the study suggest that a mobility value lower than $10^6$ $\mathrm{cm^2/Vs}$ does not prevent the formation of zero-resistance states in magnetic field in a two-dimensional system under the effect of microwave radiation.Comment: 4 pages, 2 figur

The Shapes of Flux Domains in the Intermediate State of Type-I Superconductors

In the intermediate state of a thin type-I superconductor magnetic flux penetrates in a disordered set of highly branched and fingered macroscopic domains. To understand these shapes, we study in detail a recently proposed "current-loop" (CL) model that models the intermediate state as a collection of tense current ribbons flowing along the superconducting-normal interfaces and subject to the constraint of global flux conservation. The validity of this model is tested through a detailed reanalysis of Landau's original conformal mapping treatment of the laminar state, in which the superconductor-normal interfaces are flared within the slab, and of a closely-related straight-lamina model. A simplified dynamical model is described that elucidates the nature of possible shape instabilities of flux stripes and stripe arrays, and numerical studies of the highly nonlinear regime of those instabilities demonstrate patterns like those seen experimentally. Of particular interest is the buckling instability commonly seen in the intermediate state. The free-boundary approach further allows for a calculation of the elastic properties of the laminar state, which closely resembles that of smectic liquid crystals. We suggest several new experiments to explore of flux domain shape instabilities, including an Eckhaus instability induced by changing the out-of-plane magnetic field, and an analog of the Helfrich-Hurault instability of smectics induced by an in-plane field.Comment: 23 pages, 22 bitmapped postscript figures, RevTex 3.0, submitted to Phys. Rev. B. Higher resolution figures may be obtained by contacting the author

Development of an LC-MS Method for Measuring TNF in Human Vaginal Tissue

A sensitive, accurate, and precise liquid chromatography–mass spectrometry assay for the determination of tenofovir (TNF) in human vaginal tissue was developed and validated. After homogenization of the tissue, solid-phase extraction on Varian Bond Elut-C18 column was used for sample clean up. Chromatographic separation of TNF and the internal standard (tolbutamide) was achieved with a Varian Polaris 3C18-A reversed-phase analytical column (150 mm × 2 mm). A gradient method using 0.1% formic acid in water and 0.1% formic acid in acetonitrile was employed. Detection of TNF and tolbutamide was achieved by electrospray ionization mass spectrometry in the positive ion mode using 288.05 and 271.00 m/z, respectively. Linear TNF calibration curves were obtained between 1–1,000 ng/mL with a correlation coefficient (r2) greater than 0.999. Intra-and inter-day accuracy for TNF ranged from 89.7% and 109.4% and from 97.3% and 104.9%, and precision ranged from 1.3% and 10.9% and 2.6% and 9.0%, respectively. This is the first validated method developed to quantitate TNF in human tissues